Applications of the ‘GP’ Mechanical Thrombectomy Device: Clot Removal in the Peripheral Vascular System

By Gillian Pearce, Neil Perkinson, Paul Brookfield, Julian Wong, Julian Spence, Trehana Jinsena and Luke Gwatkin.

Published by Journal of the World Universities Forum

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Article: Print $US10.00
Article: Electronic $US5.00

We present data concerning the extraction of clots using the newly invented ‘GP’ clot removal device. Both artificial clots and porcine clots of various lengths are used in plastic tube models of an artery. We investigate the pressures required to extract these clots, the times taken for extraction, together with the volumes of fluid extracted. We also investigate the use of a funnel structure on the end of the device, in terms of its impact on clot removal times, and volumes of fluid removed during the clot extraction process. Finally we present results involving clot extraction from the posterior popliteal artery of a cadaver. Our data indicated that:

•The embedded “GP” MTD appears to be the most effective device concerning the removal of both artificial and porcine blood clots compared with the end-mounted ‘GP’ MTD or the control. This result is consistent with other published data on this device.

•The ‘GP’ MTD was effective in removing clots positioned in the posterior popliteal artery of a cadavar.

•The embedded ‘GP’ device less fluid compared to the end-mounted ‘GP’ device. This is consistent with previous studies.

•There appears to be a relationship between funnel angle and pressure. Lower pressures of extraction are required for lager funnel angles mounted on the ‘GP’ device.

•Shorter times of clot extraction are required for larger funnel angles.

•We conclude that the ‘GP’ MTD is worthy of further consideration and development as a potential device for the removal of blood clots in the peripheral vascular system.

Keywords: Clot, Extraction, Artery, Tibial, Thrombectomy

Journal of the World Universities Forum, Volume 2, Issue 5, pp.11-24. Article: Print (Spiral Bound). Article: Electronic (PDF File; 1.634MB).

Dr. Gillian Pearce

Senior Lecturer, Clinical Physiology & Anatomy, Biomedical Sciences, University of Wolverhampton, Wolverhampton, West Midlands, UK

Following her Ph.D on Supernovae, Dr Pearce undertook post-doctoral research in the fields of (i) Supernovae and (ii) Solar Astrophysics. She then completed a medical degree at Oxford University and practised in the NHS for several years in the field of orthopaedics. She has undertaken research into (i) pulsars (ii) space medicine and (iii) medical inventions including Orthopaedic devices for use in theatre, a device for assisting the partially sighted, a technique for imaging plaques in arteries and a blood clot removal device for use in thromboembolic strokes. Dr Pearce is also a senior lecturer in clinical physiology and anatomy. She was a short-listed astronaut candidate for the JUNO Space mission.

Neil Perkinson

Priest, Whatangamata, New Zealand

Reverend Neil Perkinson was a technician in a radio station in Kati Kati, New Zealand, before moving to the UK to work in electronics. he then ordained as an Anglican priest and worked in the UK as priest for 13 years before returning to New Zealand (his native home)in 2008 to take up a post as parish priest in Whatangamata, New Zealand.

Paul Brookfield

Student, School of Computing and Information Technology, Wolverhampton University, West Midlands, UK

Paul Brookfield is a final year undergraduate in the school of computing and information technology, Wolverhampton University. he is studying for a degree in Computer Science.

Julian Wong

Consultant in Vascular Surgery, Vascular Surgery, City Hospital, UK

Julain Wong FRCS is a consultant in Vascular Surgery. He has a destinguished career in Vascular Surgery and is a collaborator in the development of the ‘GP’ clot removal device.

Julian Spence

Research Scientist, MIDSIM Engineering, Wolverhampton University, West Midlands, UK

Julian Spence worked as an engineer for Rolls Royce before joining MIDSIM to work as a research scientist. He is a collaborator in work involving the ‘GP’ clor removal device.

Trehana Jinsena

Student, Biomedical Sciences, Wolverhampton University, Wolverhampton, West Midlands, UK

Trehana Jinsena graduated with a degree in Biomedical sciences at Wolverhampton university.

Luke Gwatkin

Student, Biomedical Sciences, Wolverhampton University, Wolverhampton, West Midlands, UK

Luke Gwatkin is a graduate of Wolverhampton University.

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